Description

3-Thiophenecarbonylchloride,4-Ethoxy-(9Ci) is a specialized organosulfur building block, specifically an acyl chloride derivative of a substituted thiophene. This compound is valued for its high reactivity, serving as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel heterocyclic scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides that incorporate the thiophene moiety for enhanced biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed to synthesize novel thiophene-based ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules or activity-based probes for studying biological pathways and protein function.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	3-Thiophenecarbonylchloride,4-Ethoxy-(9Ci)
CAS No.	70438-01-6
Molecular Formula	C7H7ClO2S
Molecular Weight	190.65 g/mol
Synonyms	4-Ethoxy-3-thiophenecarbonyl chloride; 4-Ethoxythiophene-3-carbonyl chloride; 3-Thenoyl chloride, 4-ethoxy-; 4-Ethoxy-thiophene-3-carboxylic acid chloride; 4-Ethoxy-3-thienoyl chloride; 3-Carbonylchloride-4-ethoxythiophene
EINECS	Contact for details

Quality Control

Every batch of 3-Thiophenecarbonylchloride,4-Ethoxy-(9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.