Description

4,6-Diamino-1-(-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine CAS NO 70421-30-6 is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, offering researchers a reliable and well-characterized starting material. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism and polymerase function.
• Antiviral Agent Development: Serves as a core scaffold for designing compounds targeting viral replication mechanisms.
• Oncology Research: Investigated for its potential in creating chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Molecular Biology: Can be utilized in the study of nucleic acid interactions and the development of diagnostic probes.
• Academic & Contract Research: Essential for fundamental research in medicinal chemistry and organic synthesis within universities and CROs.

Basic Information

Product Name	4,6-Diamino-1-(-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	70421-30-6
Molecular Formula	C10H14N6O4
Molecular Weight	282.26 g/mol
Synonyms	4,6-Diamino-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine; 1-(β-D-Ribofuranosyl)-4,6-diamino-1H-pyrazolo[3,4-d]pyrimidine; 4,6-Diamino-1-(β-D-ribofuranosyl)pyrazolo[3,4-d]pyrimidine; 4,6-Diaminopyrazolopyrimidine riboside; Pyrazolo[3,4-d]pyrimidine ribonucleoside derivative; NSC 401005; 1H-Pyrazolo[3,4-d]pyrimidine, 4,6-diamino-1-β-D-ribofuranosyl-
EINECS	Contact for details

Quality Control

Our 4,6-Diamino-1-(-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.