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4-3''-o-Diacetyl-2''Deoxycytidine CAS NO 70284-47-8


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CAS No.:70284-47-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-3''-o-Diacetyl-2''Deoxycytidine is a key protected nucleoside derivative, specifically a diacetylated form of 2'-deoxycytidine. This compound is of significant value as a crucial synthetic intermediate in the production of nucleoside-based pharmaceuticals and oligonucleotides. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of antiviral drugs, anticancer agents, and other therapeutic nucleic acid analogs.

Application

  • Pharmaceutical Intermediate: A vital building block in the synthesis of active pharmaceutical ingredients (APIs) for antiviral and anticancer therapies.
  • Oligonucleotide Synthesis: Used in the preparation of modified oligonucleotides for research, diagnostics, and therapeutic applications.
  • Biochemical Research: Serves as a protected substrate in enzymatic studies and metabolic pathway investigations.
  • Prodrug Development: Utilized in the design and synthesis of prodrug forms of nucleoside analogs to improve bioavailability and stability.
  • Reference Standard: Acts as a high-purity chemical reference standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name 4-3''-o-Diacetyl-2''Deoxycytidine
CAS No. 70284-47-8
Molecular Formula C13H17N3O6
Molecular Weight 311.29 g/mol
Synonyms 2'-Deoxycytidine, 3',5'-diacetate; 3',5'-Di-O-acetyl-2'-deoxycytidine; 2'-Deoxycytidine 3',5'-diacetate; N4-Acetyl-2'-deoxycytidine 3',5'-diacetate; 1-(3,5-Di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-4-aminopyrimidin-2(1H)-one; Diacetylated deoxycytidine; Protected 2'-deoxycytidine
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Quality Control

Our 4-3''-o-Diacetyl-2''Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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