Description

(13S,14R,22R,25S)-1,15-Dioxo-5-Chloro-6β,13,20,22-Tetrahydroxy-14,17α:14,27-Diepoxy-16β,24-Cyclo-13,14-Seco-5α-Ergosta-2-Ene-18,26-Dioic Acid 18,20:26,22-Dilactone is a complex, highly functionalized ergostane-type steroidal lactone, distinguished by its unique seco-cyclo-dilactone structure. This compound serves as a critical advanced pharmaceutical intermediate and a valuable scaffold for medicinal chemistry research, enabling the synthesis of novel bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing steroidal drugs, enzyme inhibitors, and other high-value therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroidal drugs and bioactive compounds targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used as a complex molecular scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Potential use in biochemical assays to study sterol biosynthesis pathways or specific biological interactions due to its intricate structure.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Valuable starting material for synthetic chemists exploring novel ring systems and complex molecular architectures.

Basic Information

Product Name	(13S,14R,22R,25S)-1,15-Dioxo-5-Chloro-6β,13,20,22-Tetrahydroxy-14,17α:14,27-Diepoxy-16β,24-Cyclo-13,14-Seco-5α-Ergosta-2-Ene-18,26-Dioic Acid 18,20:26,22-Dilactone
CAS No.	70241-09-7
Molecular Formula	C₂₈H₃₃ClO₁₂
Molecular Weight	621.01 g/mol
Synonyms	5-Chloro-6β,13,20,22-tetrahydroxy-1,15-dioxo-14,17α:14,27-diepoxy-16β,24-cyclo-13,14-seco-5α-ergosta-2-ene-18,26-dioic acid 18,20:26,22-dilactone; 5-Chloro-6β,13,20,22-tetrahydroxy-1,15-dioxo-14,17α:14,27-diepoxy-16β,24-cyclo-13,14-secoergosta-2-ene-18,26-dioic acid 18,20:26,22-dilactone; 70241-09-7; 5α-Ergosta-2-ene-18,26-dioic acid, 5-chloro-6β,13,20,22-tetrahydroxy-1,15-dioxo-14,17α:14,27-diepoxy-16β,24-cyclo-13,14-seco-, 18,20:26,22-dilactone, (13S,14R,22R,25S)-; UNII-2Q8Q4T9F3W
EINECS	Contact for details

Quality Control

Our (13S,14R,22R,25S)-1,15-Dioxo-5-Chloro-6β,13,20,22-Tetrahydroxy-14,17α:14,27-Diepoxy-16β,24-Cyclo-13,14-Seco-5α-Ergosta-2-Ene-18,26-Dioic Acid 18,20:26,22-Dilactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) detailing all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.