Description

n-Methyldopa is a synthetic amino acid derivative and a key pharmaceutical intermediate. Its primary commercial value lies in its role as a precursor in the synthesis of critical active pharmaceutical ingredients (APIs), particularly in the cardiovascular therapeutic class. This compound is essential for manufacturers in the pharmaceutical and fine chemical sectors requiring high-purity building blocks for complex drug synthesis.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of L-Dopa (Levodopa) and related dopaminergic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key starting material or intermediate in the multi-step production of cardiovascular and neurological drugs.
• Biochemical Research: Used in laboratory settings for studying catecholamine metabolism, neurotransmission, and enzyme inhibition studies.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Process Development: Utilized in R&D for optimizing synthetic routes and scaling up production processes for related pharmaceutical compounds.

Basic Information

Product Name	n-Methyldopa
CAS No.	70152-53-3
Molecular Formula	C10H13NO4
Molecular Weight	211.22 g/mol
Synonyms	3-(3,4-Dihydroxyphenyl)-2-methylalanine; α-Methyldopa; L-α-Methyldopa; MK-351; Aldomet Intermediate; Methyldopa Impurity; (2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
EINECS	Contact for details

Quality Control

Our n-Methyldopa is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, IR, and titration. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.