Description

4-Chloro-3-Sulfamoylbenzoyl Chloride is a high-purity, reactive benzoyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a sulfonamide and an acid chloride group, makes it an indispensable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based diuretics, carbonic anhydrase inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the sulfamoyl moiety for bioactivity.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing specialized azo dyes and pigments requiring chlorinated benzoyl structures.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polyamides and polyesters with specific functional groups.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new reaction pathways and creating compound libraries.
• Ligand Synthesis: Used to prepare complexing agents and chelators for analytical and catalytic applications.

Basic Information

Product Name	4-Chloro-3-Sulfamoylbenzoyl Chloride
CAS No.	70049-77-3
Molecular Formula	C7H5Cl2NO3S
Molecular Weight	254.09 g/mol
Synonyms	3-(Aminosulfonyl)-4-chlorobenzoyl Chloride; 4-Chloro-3-sulfamoylbenzoic acid chloride; Benzoic acid, 4-chloro-3-sulfamoyl-, chloride; 4-Chloro-3-sulphamoylbenzoyl Chloride; 4-Chloro-3-sulfamoyl-benzoylchlorid; 4-Chloro-3-sulfamoylbenzoyl chloride (CAS 70049-77-3)
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Sulfamoylbenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	142°C - 147°C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.