Description

5-Ethyluracil Arabinoside is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and intermediate for the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in nucleoside chemistry. The material's specific structure allows for targeted modifications in drug discovery programs aimed at therapeutic nucleosides.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of experimental antiviral and antineoplastic (anticancer) nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Agent Development: Investigated for potential activity against a range of viral targets due to its modified arabinoside structure.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Used in scaling up the production of more complex nucleoside-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Ethyluracil Arabinoside
CAS No.	70020-72-3
Molecular Formula	C11H14N2O6
Molecular Weight	270.24 g/mol
Synonyms	1-β-D-Arabinofuranosyl-5-ethyluracil; 5-Ethyl-1-β-D-arabinofuranosyluracil; 5-EthylaraU; 5-Ethyl-1-β-D-arabinofuranosyl-2,4(1H,3H)-pyrimidinedione; Ara-5-EtU; β-D-Arabinofuranoside, 5-ethyl-1-(2,4(1H,3H)-pyrimidinedion-1-yl)-; 5-EU-Ara
EINECS	Contact for details

Quality Control

Our 5-Ethyluracil Arabinoside is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity biochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.