Description

6-o-Methyl Guanosine is a chemically modified nucleoside derivative of guanosine, featuring a methyl group at the 6-oxygen position. This specific modification is crucial for research in nucleic acid chemistry, epigenetics, and as a reference standard in analytical applications. It serves as a valuable building block and biochemical tool for pharmaceutical R&D, academic research, and diagnostic development. The compound is supplied with a commitment to high purity and batch-to-batch consistency for reliable experimental results.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and study of novel nucleoside-based therapeutics, including antiviral and anticancer agents.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate methyltransferase activity and RNA/DNA modification processes.
• Analytical Chemistry: Employed as a high-purity certified reference material (CRM) for method development, calibration, and quality control in HPLC, LC-MS, and other analytical techniques.
• Epigenetics Studies: Utilized in research exploring post-transcriptional modifications of RNA and their role in gene expression regulation.
• Diagnostic Reagent Manufacturing: Acts as a raw material or component in the production of diagnostic kits and assays for research use only (RUO).
• Academic & Institutional Laboratories: A fundamental reagent for teaching and advanced research in chemistry, molecular biology, and medicinal chemistry departments.

Basic Information

Product Name	6-o-Methyl Guanosine
CAS No.	7803-88-5
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	6-O-Methylguanosine; Guanosine, 6-methyl ether; 6-Methoxyguanosine; 2-Amino-6-methoxy-9-β-D-ribofuranosylpurine; 9-β-D-Ribofuranosyl-2-amino-6-methoxypurine; N6-O-Methylguanosine; 6-OMe-Guo
EINECS	Contact for details

Quality Control

Every batch of 6-o-Methyl Guanosine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Specifications can be aligned with research-grade or analytical reference standard requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.