Description

3,4,6-Tri-o-Acetyl-2-Deoxy-2-Fluoro-D-Mannopyranosyl Fluoride is a key fluorinated carbohydrate building block, specifically a glycosyl fluoride donor. This compound matters for its critical role in the stereoselective synthesis of complex oligosaccharides and glycoconjugates, enabling precise control over glycosidic bond formation. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and advanced materials where specific sugar motifs are essential. The CAS number for this compound is provided in the table below.

Application

• Glycosylation Reagent: A crucial donor molecule in the stereocontrolled chemical synthesis of oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and development of fluorinated nucleoside analogs and other carbohydrate-based active pharmaceutical ingredients (APIs).
• Probe Development: Serves as a precursor for synthesizing fluorinated sugar probes used in metabolic labeling and imaging studies.
• Glycoconjugate Synthesis: Enables the construction of glycopeptides, glycolipids, and other biologically relevant conjugates for immunological studies.
• Chemical Biology Research: A valuable tool for investigating glycosyltransferase mechanisms and carbohydrate-protein interactions.
• Material Science: Potential building block for creating novel fluorinated polymers or surface coatings with unique properties.

Basic Information

Product Name	3,4,6-Tri-o-Acetyl-2-Deoxy-2-Fluoro-D-Mannopyranosyl Fluoride
CAS No.	7772-87-4
Molecular Formula	C12H16F2O8
Molecular Weight	326.25 g/mol
Synonyms	2-Deoxy-2-fluoro-3,4,6-tri-O-acetyl-α-D-mannopyranosyl fluoride; Tri-O-acetyl-2-deoxy-2-fluoro-D-mannopyranosyl fluoride; 2-Fluoro-2-deoxy-3,4,6-tri-O-acetyl-α-D-mannopyranosyl fluoride; α-D-Mannopyranosyl fluoride, 2-deoxy-2-fluoro-, 3,4,6-triacetate; Fluorinated mannosyl fluoride donor; Glycosyl fluoride donor
EINECS	Contact for details

Quality Control

Our 3,4,6-Tri-o-Acetyl-2-Deoxy-2-Fluoro-D-Mannopyranosyl Fluoride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity, meeting the exacting standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.