Description

14,21-Cyclo-17.Alpha.-Pregna-5,20-Diene-16.Alpha.-Carboxylic Acid, 17-Acetyl-3.Beta.-Hydroxy-, Acetate is a high-purity, structurally complex steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or reference standard for the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized steroid-based molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control of related steroid compounds in research and manufacturing.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor-ligand interactions.
• Process Chemistry Development: Serves as a model compound for optimizing complex organic synthesis routes, including cyclization and functional group transformations.
• Academic Research: Utilized in university and institutional labs for exploratory chemistry and the development of new synthetic methodologies.

Basic Information

Item	Details
Product Name	14,21-Cyclo-17.Alpha.-Pregna-5,20-Diene-16.Alpha.-Carboxylic Acid, 17-Acetyl-3.Beta.-Hydroxy-, Acetate
CAS No.	7732-49-2
Molecular Formula	C26H34O5
Molecular Weight	426.55 g/mol
Synonyms	17-Acetyl-3β-hydroxy-14,21-cyclo-17α-pregna-5,20-diene-16α-carboxylic acid acetate; 14,21-Cyclo-17α-pregna-5,20-diene-16α-carboxylic acid, 17-acetyl-3β-hydroxy-, acetate; 3β-Acetoxy-17-acetyl-14,21-cyclo-17α-pregna-5,20-diene-16α-carboxylic acid; 17α-Pregna-5,20-diene-16α-carboxylic acid, 17-acetyl-3β-hydroxy-14,21-cyclo-, acetate; Cyclic steroid acetate derivative; 7732-49-2; (3β,17α)-17-Acetyl-3-(acetyloxy)-14,21-cyclo-5,20-pregnadiene-16-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 14,21-Cyclo-17.Alpha.-Pregna-5,20-Diene-16.Alpha.-Carboxylic Acid, 17-Acetyl-3.Beta.-Hydroxy-, Acetate adheres to stringent quality protocols suitable for research and development applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from HPLC, NMR, and mass spectrometry are provided to support your research integrity and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.