Description

Nor Lidocaine Hydrochloride is a key pharmaceutical intermediate and analytical reference standard, chemically related to the widely used local anesthetic lidocaine. This compound is essential for research, quality control, and the synthesis of specialized medicinal agents, offering a high-purity building block for advanced pharmaceutical development. It is primarily utilized by research institutions, analytical laboratories, and manufacturers in the pharmaceutical and life sciences sectors for method development, impurity profiling, and chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of lidocaine analogs and other specialized anesthetic or antiarrhythmic agents.
• Analytical Reference Standard: Used in quality control laboratories for the identification and quantification of lidocaine and its related substances via HPLC, GC, or other chromatographic methods.
• Metabolite Studies: Employed in pharmacological and toxicological research to study the metabolism and degradation pathways of lidocaine.
• Impurity Profiling: Essential for characterizing and controlling process-related impurities in lidocaine hydrochloride API manufacturing, ensuring compliance with pharmacopeial standards (e.g., USP, EP).
• Chemical Research: Used as a model compound in organic synthesis and medicinal chemistry research to explore structure-activity relationships (SAR).
• Method Development & Validation: Acts as a known component for developing and validating analytical methods in compliance with ICH guidelines.

Basic Information

Product Name	Nor Lidocaine Hydrochloride
CAS No.	7729-94-4
Molecular Formula	C13H21ClN2O
Molecular Weight	256.77 g/mol
Synonyms	2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride; Lidocaine Impurity A Hydrochloride; Norlidocaine HCl; Desethyllidocaine Hydrochloride; Lignocaine Impurity A HCl; 2,6-Xylidide, N-(diethylglycyl)-, hydrochloride; α-Diethylamino-2,6-dimethylacetanilide hydrochloride
EINECS	Contact for details

Quality Control

Our Nor Lidocaine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profile determination via validated methods such as HPLC and titration, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.