Description

Chlorisondamine is a potent ganglionic blocking agent and a quaternary ammonium compound of significant pharmacological interest. Its primary value lies in its historical and research use as a model compound for studying autonomic nervous system function and nicotinic acetylcholine receptors. This chemical is essential for researchers and developers in the pharmaceutical and life sciences sectors, particularly those focused on neuropharmacology, cardiovascular research, and the development of autonomic nervous system modulators.

Application

• Pharmacological Research: Used as a standard ganglionic blocker in experimental studies to investigate autonomic nervous system pathways and hemodynamics.
• Neurochemical Studies: Serves as a reference compound for research on nicotinic acetylcholine receptors (nAChRs) in both central and peripheral nervous systems.
• Cardiovascular Research: Employed in preclinical models to study blood pressure regulation and the effects of sympathetic and parasympathetic blockade.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: A key reagent for universities and research institutes conducting fundamental studies in physiology and pharmacology.
• Chemical Intermediate: Can serve as a synthetic building block for the preparation of more complex quaternary ammonium compounds with specialized biological activity.

Basic Information

Product Name	Chlorisondamine
CAS No.	7701-62-4
Molecular Formula	C14H20Cl2N6
Molecular Weight	343.26 g/mol
Synonyms	4,5,6,7-Tetrachloro-2-(2-dimethylaminoethyl)-2H-isoindoline-1,3-dione dimethochloride; Chlorisondamine Chloride; Ecolid; Su-3088; Ismelin (component); 2-(2-Dimethylaminoethyl)-4,5,6,7-tetrachloroisoindoline-1,3-dione dimethochloride
EINECS	Contact for details

Quality Control

Our Chlorisondamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.