Description

4-Bromophenyl Chloroformate is a versatile and highly reactive organic synthesis intermediate. This compound is crucial for the efficient introduction of the 4-bromophenyloxycarbonyl protecting group, enabling precise chemical transformations. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), advanced materials, and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of carbamate and carbonate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Peptide Chemistry: Used as a reagent for the temporary protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Agrochemical Synthesis: Intermediate in the production of herbicides, fungicides, and insecticides that contain the 4-bromophenyl moiety.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Material Science: Employed in the surface functionalization of materials and the synthesis of advanced organic frameworks.
• Chemical Research: A valuable reagent in organic synthesis laboratories for constructing complex molecular architectures.

Basic Information

Product Name	4-Bromophenyl Chloroformate
CAS No.	7693-44-9
Molecular Formula	C7H4BrClO2
Molecular Weight	235.46 g/mol
Synonyms	p-Bromophenyl Chloroformate; 4-Bromophenyl Carbonochloridate; Chloroformic Acid 4-Bromophenyl Ester; (4-Bromophenoxy)carbonyl Chloride; Carbonochloridic Acid, 4-Bromophenyl Ester; p-Bromophenoxycarbonyl Chloride
EINECS	Contact for details

Quality Control

Our 4-Bromophenyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.