Description

[3,4-Diacetyloxy-5-(6-Sulfanylidene-3H-Purin-9-Yl)Oxolan-2-Yl]Methyl A Cetate is a high-purity, modified nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel antiviral and anticancer agents, particularly in the development of nucleotide analogs. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality building blocks for complex molecular synthesis. The material's specific structure offers a versatile platform for further chemical modifications aimed at enhancing drug efficacy and selectivity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Antiviral Drug Research: Used in the R&D of nucleotide analogs targeting viral polymerases for diseases such as hepatitis and herpes.
• Oncology Research: Serves as a precursor in the development of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Probe Development: Utilized to create labeled or modified nucleotides for studying enzymatic mechanisms and cellular processes.
• Precision Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Provides a specialized reagent for universities and research institutes exploring nucleotide chemistry and medicinal chemistry.

Basic Information

Product Name	[3,4-Diacetyloxy-5-(6-Sulfanylidene-3H-Purin-9-Yl)Oxolan-2-Yl]Methyl A Cetate
CAS No.	7687-42-5
Molecular Formula	C16H18N4O8S
Molecular Weight	426.40 g/mol
Synonyms	9-[(2R,3R,4R,5R)-3,4-Diacetoxy-5-(acetoxymethyl)oxolan-2-yl]-6-sulfanylidene-3H-purin-2-one; 6-Mercaptopurine 2',3',5'-Triacetate; 6-Thioxopurine Riboside Triacetate; 6-Thiouridine Triacetate; 2',3',5'-Tri-O-acetyl-6-thiouridine; 6-Mercapto-9-β-D-ribofuranosylpurine 2',3',5'-triacetate; S6-2',3',5'-Tri-O-acetyl-6-thiouridine; 6-Thio-UTP Triacetate Derivative
EINECS	Contact for details

Quality Control

Our [3,4-Diacetyloxy-5-(6-Sulfanylidene-3H-Purin-9-Yl)Oxolan-2-Yl]Methyl A Cetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and potential cGMP starting material standards. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.