Description

4-(N,n-Dimethylamino)Azobenzene-4'-Isothiocyanate is a specialized organic reagent featuring a reactive isothiocyanate group linked to a dimethylaminoazobenzene chromophore. This unique bifunctional structure makes it a critical component for labeling and detection in advanced biochemical and analytical applications. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic industries for covalent conjugation to biomolecules.

Application

• Bioconjugation Reagent: For covalent labeling of proteins, antibodies, and peptides via reaction with primary amines or thiol groups.
• Fluorescent Probe Synthesis: Acts as a precursor or active component in the development of chromogenic and fluorescent probes for bioimaging.
• Affinity Chromatography Ligand: Used to functionalize solid supports for the purification of specific biomolecules.
• Diagnostic Assay Development: Employed in the creation of enzyme-linked immunosorbent assays (ELISAs) and other immunoassays.
• Chemical Biology Research: A tool for studying protein structure, function, and interactions through site-specific tagging.
• Material Science: Surface modification of polymers and nanoparticles for biomedical applications.

Basic Information

Product Name	4-(N,n-Dimethylamino)Azobenzene-4'-Isothiocyanate
CAS No.	7612-98-8
Molecular Formula	C15H14N4S
Molecular Weight	282.36 g/mol
Synonyms	DABITC; 4-(Dimethylamino)azobenzene-4'-isothiocyanate; 4-Isothiocyanato-4'-(dimethylamino)azobenzene; 4-Dimethylaminoazobenzene-4'-isothiocyanate; N,N-Dimethyl-4-[(4-isothiocyanatophenyl)azo]aniline; p-(Dimethylamino)azobenzene isothiocyanate; DABITC Reagent; 1-Isothiocyanato-4-[[4-(dimethylamino)phenyl]azo]benzene
EINECS	Contact for details

Quality Control

Our 4-(N,n-Dimethylamino)Azobenzene-4'-Isothiocyanate is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions may lead to degradation. Keep container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetone

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.