Description

7-Ketocholestanol is a significant oxidized derivative of cholesterol, serving as a key intermediate in the study of sterol metabolism and oxidative pathways. This compound is valued for its role as a reference standard and a synthetic precursor in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on lipid chemistry, metabolic disease models, and the synthesis of specialized steroidal compounds.

Application

• Biochemical Research Standard: Used as a high-purity reference material in analytical methods (HPLC, GC-MS) for quantifying sterol oxidation products in biological samples.
• Metabolic Pathway Studies: A critical tool for investigating cholesterol oxidation mechanisms, atherogenesis, and the biological activity of oxysterols.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex steroidal molecules for drug discovery programs.
• Diagnostic Development: Employed in the development and calibration of diagnostic assays targeting specific oxysterol biomarkers associated with metabolic disorders.
• Academic Research: Utilized in university and institutional labs for fundamental studies on lipid peroxidation, cell membrane integrity, and oxidative stress.
• Fine Chemical Synthesis: Acts as a starting material or intermediate for producing customized sterol derivatives and specialty chemicals.

Basic Information

Product Name	7-Ketocholestanol
CAS No.	7591-17-5
Molecular Formula	C₂₇H₄₆O₂
Molecular Weight	402.66 g/mol
Synonyms	7-Oxocholestanol; 5-Cholestan-3β-ol-7-one; 3β-Hydroxy-5-cholestan-7-one; 7-Ketocholestanol; 7-Keto-5-cholestanol; 7-Oxo-5-cholestan-3β-ol; Cholestan-7-one-3β-ol
EINECS	Contact for details

Quality Control

Our 7-Ketocholestanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This product is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.