Description

2-Bromophenylphosphonic Acid is a versatile organophosphorus compound featuring both a bromine substituent and a phosphonic acid functional group on the aromatic ring. This unique structure makes it a valuable key intermediate in the synthesis of complex molecules, particularly in advanced material science and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for constructing ligands, metal-organic frameworks (MOFs), and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, especially those targeting kinase inhibition or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the bromophenyl moiety imparts specific biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for phosphonate-based ligands used in homogeneous catalysis and metal complexation for various organic transformations.
• Material Science Research: Employed in the creation of functionalized monomers for polymers, flame retardants, and corrosion inhibitors.
• Metal-Organic Frameworks (MOFs): The phosphonic acid group enables its use as a linker molecule in constructing porous coordination polymers with tailored properties for gas storage or separation.
• Chemical Synthesis Reagent: Utilized in Suzuki-Miyaura and other cross-coupling reactions as a functionalized aryl halide component.

Basic Information

Product Name	2-Bromophenylphosphonic Acid
CAS No.	7506-82-3
Molecular Formula	C6H6BrO3P
Molecular Weight	236.99 g/mol
Synonyms	(2-Bromophenyl)phosphonic Acid; o-Bromophenylphosphonic Acid; Phosphonic Acid, P-(2-Bromophenyl)-; 2-Bromobenzene phosphonic acid; (o-Bromophenyl)phosphonic acid; 7506-82-3; NSC 163081
EINECS	Contact for details

Quality Control

Our 2-Bromophenylphosphonic Acid is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by HPLC, NMR, and titration methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.