Description

[4,5-Diacetyloxy-6-(Acetyloxymethyl)-2-(4-Methoxy-2-Oxo-Pyrimidin-1-Yl)Oxan-3-Yl] 2,2,2-Trichloroacetate is a sophisticated nucleoside derivative, a key building block in advanced pharmaceutical synthesis. Its value lies in its role as a protected intermediate, enabling precise chemical modifications essential for developing novel therapeutic agents. This high-purity compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral drugs, anticancer therapies, and other nucleoside-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of modified nucleoside analogs for antiviral and anticancer applications.
• Antiviral Drug Research: Used in the research and development of next-generation antiviral agents targeting viruses such as hepatitis and herpes.
• Oncology Research: Serves as a key synthon for creating nucleoside-based chemotherapeutic agents and prodrugs.
• Biochemical Research: Employed in studies of enzyme mechanisms, nucleic acid chemistry, and as a tool compound in molecular biology.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) under GMP conditions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs specializing in complex molecule manufacturing.

Basic Information

Item	Details
Product Name	[4,5-Diacetyloxy-6-(Acetyloxymethyl)-2-(4-Methoxy-2-Oxo-Pyrimidin-1-Yl)Oxan-3-Yl] 2,2,2-Trichloroacetate
CAS No.	7506-40-3
Molecular Formula	C19H21Cl3N2O11
Molecular Weight	559.73 g/mol
Synonyms	1-(3-O-(Trichloroacetyl)-2,5-di-O-acetyl-β-D-ribofuranosyl)thymine; 2'-Deoxythymidine 3',5'-diacetate 3'-(trichloroacetate); 1-[3-O-(Trichloroacetyl)-2,5-di-O-acetyl-β-D-ribofuranosyl]-5-methyluracil; Thymidine 3',5'-di-O-acetyl-3'-O-(trichloroacetyl); 5-Methyluridine derivative, 3',5'-diacetate 3'-(trichloroacetate); Protected thymidine intermediate; Trichloroacetylated thymidine derivative
EINECS	Contact for details

Quality Control

Every batch of our [4,5-Diacetyloxy-6-(Acetyloxymethyl)-2-(4-Methoxy-2-Oxo-Pyrimidin-1-Yl)Oxan-3-Yl] 2,2,2-Trichloroacetate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and purity. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.