Description

27-Nor-25-Ketocholesterol is a high-purity steroidal ketone derivative, identified by CAS NO 7494-34-0. This compound serves as a critical advanced intermediate and reference standard in pharmaceutical research and development. It is primarily required by research institutions and pharmaceutical companies engaged in the synthesis and study of steroid hormones, metabolic pathways, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies investigating cholesterol metabolism, enzyme inhibition, and receptor binding assays.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development and validation in analytical laboratories (HPLC, GC-MS).
• Metabolite Studies: Employed in the research of steroid biosynthesis and catabolism pathways to identify and characterize metabolic products.
• Academic Synthesis: Utilized in university and institutional laboratories for teaching and research in advanced organic and medicinal chemistry.

Basic Information

Product Name	27-Nor-25-Ketocholesterol
CAS No.	7494-34-0
Molecular Formula	C₂₆H₄₂O₂
Molecular Weight	386.62 g/mol
Synonyms	25-Keto-27-norcholesterol; 27-Norcholest-5-en-3β-ol-25-one; 25-Oxo-27-norcholesterol; (3β)-25-Oxo-27-norcholest-5-en-3-ol; 27-Nor-25-oxocholesterol; 25-Ketocholesterol, 27-nor-; 27-Nor-5-cholesten-3β-ol-25-one
EINECS	Contact for details

Quality Control

Our 27-Nor-25-Ketocholesterol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.