Description

Thyroxine is a critical iodinated amino acid hormone, also known as T4, which serves as the primary prohormone secreted by the thyroid gland. Its consistent high purity is essential for reliable performance in pharmaceutical formulations and life science research. This compound is vital for manufacturers and researchers in the pharmaceutical, biotechnology, and diagnostic sectors, where it is used as an active pharmaceutical ingredient (API) and a key biochemical standard.

Application

• Active Pharmaceutical Ingredient (API): Core component in the manufacture of thyroid hormone replacement therapies (e.g., Levothyroxine Sodium).
• Biochemical Research: Used as a standard and reagent in studies of thyroid function, hormone metabolism, and endocrine signaling pathways.
• Diagnostic Kit Production: Serves as a critical calibrator and component in immunoassays and test kits for measuring thyroid-stimulating hormone (TSH) and T4 levels.
• Veterinary Pharmaceuticals: Employed in formulations for treating hypothyroidism in companion animals and livestock.
• Reference Standard: Used in quality control laboratories for the identification and assay of thyroxine in raw materials and finished products.

Basic Information

Product Name	Thyroxine
CAS No.	7488-70-2
Molecular Formula	C15H11I4NO4
Molecular Weight	776.87 g/mol
Synonyms	L-Thyroxine; T4; Levothyroxine; 3,5,3',5'-Tetraiodo-L-thyronine; (2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid; Thyroxin; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
EINECS	231-283-6

Quality Control

Our Thyroxine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.