Description

Guanabenz CAS NO 7473-70-3 is a selective α-2 adrenergic receptor agonist with significant pharmacological activity. This compound is a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and is valued for its role in central nervous system research and drug development. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of antihypertensive agents and neurological therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Guanabenz acetate, an active pharmaceutical ingredient (API) used as an antihypertensive agent.
• Neurological Research: Employed in preclinical studies to investigate α-2 adrenergic receptor pathways and their effects on the central nervous system.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Research: Used in studies exploring cellular stress responses, including the unfolded protein response (UPR) pathway.
• Drug Discovery: A valuable compound for screening and developing new therapeutic agents targeting adrenergic receptors.

Basic Information

Product Name	Guanabenz
CAS No.	7473-70-3
Molecular Formula	C8H8Cl2N4
Molecular Weight	231.08 g/mol
Synonyms	2,6-Dichlorobenzylideneamino guanidine; (2,6-Dichlorobenzylidene)amino guanidine; Guanabenz base; Wy-8678; NSC 113371; Benzylideneamino guanidine derivative; 1-[(2,6-Dichlorophenyl)methylene]amino]guanidine
EINECS	231-268-8

Quality Control

Our Guanabenz is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates and research chemicals. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.