Description

5α-Androstane-1α,17β-Diol is a high-purity, synthetic steroid diol derivative of androstane. This compound serves as a critical pharmaceutical intermediate and a valuable reference standard in analytical chemistry and research. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and life sciences sectors for the development and quality control of steroidal drugs and biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex steroidal active pharmaceutical ingredients (APIs) and hormone analogs.
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, GC-MS, and other chromatographic analyses within pharmaceutical QC/QA laboratories.
• Biochemical Research: Employed in metabolic pathway studies, enzyme inhibition assays, and as a probe to investigate androgen receptor interactions and steroidogenesis.
• Life Science Reagent: Serves as a purified reagent for in-vitro and preclinical studies in endocrinology and developmental biology.

Basic Information

Product Name	5α-Androstane-1α,17β-Diol
CAS No.	7417-23-4
Molecular Formula	C19H32O2
Molecular Weight	292.46 g/mol
Synonyms	1α,17β-Dihydroxy-5α-androstane; 5α-Androstane-1α,17β-diol; Androstanediol; 1α,17β-Androstanediol; 17β-Hydroxy-5α-androstan-1α-ol; NSC 11336; 1α,17β-Dihydroxyandrostane
EINECS	Contact for details

Quality Control

Our 5α-Androstane-1α,17β-Diol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC, to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.