Description

3'-Amino-2',3'-Dideoxyadenosine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and intermediate for the synthesis of novel antiviral and anticancer agents, particularly nucleoside reverse transcriptase inhibitors. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of therapeutic nucleotides. The product is supplied with a high level of purity to meet the stringent requirements of advanced biochemical applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of antiviral drugs, especially those targeting HIV and other retroviruses.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Anticancer Agent Development: Serves as a core structure for designing novel nucleoside analogs that interfere with DNA synthesis in rapidly dividing cells.
• Pro-drug Synthesis: Utilized in the creation of pro-drug forms to enhance the bioavailability and targeting of active nucleoside therapeutics.
• Molecular Biology Tools: Can be incorporated into oligonucleotides to study structure-activity relationships or to create modified probes.

Basic Information

Product Name	3'-Amino-2',3'-Dideoxyadenosine
CAS No.	7403-25-0
Molecular Formula	C10H14N6O2
Molecular Weight	250.26 g/mol
Synonyms	3'-Amino-2',3'-dideoxyadenosine; 9-[(2R,5S)-5-Amino-5-deoxy-β-D-ribofuranosyl]adenine; 3'-Amino-2',3'-ddA; 3'-Amino-ddA; 3'-Amino-2',3'-dideoxy-D-adenosine; 3'-Amino-2',3'-dideoxyadenosine (CAS 7403-25-0); 3'-Amino-ddAdo
EINECS	Contact for details

Quality Control

Our 3'-Amino-2',3'-Dideoxyadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.