Description

1-[(4-Isothiocyanatophenyl)Sulfonyl]Piperidine is a specialized organic building block featuring a reactive isothiocyanate group linked to a sulfonylpiperidine scaffold. This compound matters for its role as a versatile intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and protease inhibitor research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides requiring specific sulfonyl and thiourea motifs.
• Bioconjugation & Probe Development: The reactive isothiocyanate group allows for covalent coupling to amines in proteins, antibodies, or other biomolecules for creating diagnostic probes or targeted conjugates.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers with specific thermal or chemical resistance properties.
• Chemical Biology Tool: Utilized in activity-based protein profiling (ABPP) and other chemoproteomic approaches to label and study enzyme families.

Basic Information

Product Name	1-[(4-Isothiocyanatophenyl)Sulfonyl]Piperidine
CAS No.	7356-55-0
Molecular Formula	C12H12N2O2S2
Molecular Weight	280.36 g/mol
Synonyms	4-Isothiocyanatobenzenesulfonamide, N-piperidyl-; 1-[(4-Isothiocyanatophenyl)sulfonyl]piperidine; 4-(Piperidine-1-sulfonyl)phenyl isothiocyanate; Piperidine, 1-[(4-isothiocyanatophenyl)sulfonyl]-; 7356-55-0; 4-Piperidinosulfonylphenyl isothiocyanate; 1-(4-Isothiocyanato-benzenesulfonyl)-piperidine
EINECS	Contact for details

Quality Control

Our 1-[(4-Isothiocyanatophenyl)Sulfonyl]Piperidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.