Description

Morpholinophosphonic Acid 5'-Adenosyl Ester is a specialized biochemical intermediate, a nucleotide analog featuring a morpholino phosphoramidate linkage. This compound is critical for researchers and manufacturers requiring high-purity building blocks for oligonucleotide synthesis and biochemical studies. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for applications in drug discovery, molecular biology, and the development of advanced therapeutic modalities.

Application

• Oligonucleotide Synthesis: Serves as a key phosphoramidate monomer or modified nucleotide precursor in the solid-phase synthesis of morpholino oligomers and other antisense therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, polymerases, and other nucleotide-processing enzymes.
• Pharmaceutical Development: Acts as an intermediate in the synthesis of prodrugs and novel antiviral or anticancer nucleotide analogs.
• Proteomics & Genomics: Employed in the development of probes and tools for gene silencing, mRNA targeting, and diagnostic assays.
• Chemical Biology: Utilized to study cellular signaling pathways and metabolic processes involving adenosine derivatives.

Basic Information

Product Name	Morpholinophosphonic Acid 5'-Adenosyl Ester
CAS No.	7331-13-7
Molecular Formula	C14H21N6O7P
Molecular Weight	416.33 g/mol
Synonyms	5'-O-[N-(Morpholino)phosphono]adenosine; Adenosine 5'-(N-morpholinophosphonate); Morpholino Adenosine Phosphoramidate; 5'-Adenylic Acid, Morpholino-; 7331-13-7; Adenosine, 5'-[N-(morpholino)phosphonate]; Adenosine 5'-Morpholinophosphonate
EINECS	Contact for details

Quality Control

Our production of Morpholinophosphonic Acid 5'-Adenosyl Ester adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.