Description

5-Bromo-1-Benzothiophene-2-Carbonyl Chloride is a versatile and highly reactive organic intermediate crucial for advanced chemical synthesis. Its value lies in its ability to act as a key building block for constructing complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working in the fields of medicinal chemistry, material science, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold for biological activity.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Ligand and Catalyst Development: Employed to synthesize specialized ligands for transition metal catalysis and organocatalysts used in asymmetric synthesis.
• Fluorescent Dye and Sensor Precursor: Utilized in the production of fluorophores and molecular probes for bio-imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-1-Benzothiophene-2-Carbonyl Chloride
CAS No.	7312-14-3
Molecular Formula	C9H4BrClOS
Molecular Weight	275.55 g/mol
Synonyms	5-Bromobenzo[b]thiophene-2-carbonyl chloride; 5-Bromo-1-benzothiophene-2-carboxylic acid chloride; 2-Benzothiophenecarbonyl chloride, 5-bromo-; 5-Bromobenzo[b]thiophene-2-carbonyl chloride; 5-Bromothianaphthene-2-carbonyl chloride; 5-Bromo-benzo[b]thiophene-2-carbonyl chloride; 7312-14-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Benzothiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.