Description

1,11(4H,5H)-Naphthacenedione, 2-Acetyl-7-Chloro-4-(Dimethylamino)-4A,5A,6,12A-Tetrahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-, [4S-(4α,4Aα,5Aα,6β,12Aα)]- (9Ci) is a complex, stereochemically defined naphthacenedione derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate polycyclic structure, featuring multiple functional groups including acetyl, chloro, dimethylamino, and hydroxyl substituents, makes it a valuable high-purity building block for developing novel chemical entities. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for use in targeted synthesis programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new therapeutic agents, particularly for complex molecule synthesis.
• Chemical Research: Used as a specialized reagent in academic and industrial laboratories for studying structure-activity relationships (SAR) and novel reaction pathways.
• Agrochemical Development: Acts as a potential intermediate in the synthesis of advanced, biologically active compounds for crop protection.
• Dye and Pigment Research: Its naphthacenedione core makes it a candidate for investigation in the development of specialized dyes or functional colorants.
• Material Science: Investigated for potential use in creating organic electronic materials or advanced polymers due to its conjugated system.

Basic Information

Product Name	1,11(4H,5H)-Naphthacenedione, 2-Acetyl-7-Chloro-4-(Dimethylamino)-4A,5A,6,12A-Tetrahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-, [4S-(4α,4Aα,5Aα,6β,12Aα)]- (9Ci)
CAS No.	7301-38-4
Molecular Formula	C₂₁H₂₄ClNO₈
Molecular Weight	453.87 g/mol
Synonyms	2-Acetyl-7-chloro-4-(dimethylamino)-4a,5a,6,12a-tetrahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11(4H,5H)-naphthacenedione; Aclacinomycin A aglycone; Aclarubicin aglycone; (4S,4aS,5aS,6R,12aS)-2-Acetyl-7-chloro-4-(dimethylamino)-4a,5a,6,12a-tetrahydro-3,6,10,12,12a-pentahydroxy-6-methyl-4,11-dihydrotetracene-1,5,8,13-tetrone; 7301-38-4; Aclacinomycinone; Aclarubicinone
EINECS	Contact for details

Quality Control

Our high-purity 1,11(4H,5H)-Naphthacenedione derivative is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.