Description

UDP-GalNAc (Uridine diphosphate N-acetylgalactosamine) is a critical nucleotide sugar donor essential for the biosynthesis of glycoproteins and proteoglycans. Its primary commercial value lies in its role as a high-purity substrate for enzymatic glycosylation reactions, particularly in the synthesis of O-linked glycans. This compound is indispensable for research and production in glycobiology, biopharmaceutical development, and the manufacture of complex therapeutic proteins.

Application

• Glycoprotein Synthesis: As a key substrate for glycosyltransferases in the enzymatic synthesis of O-linked glycoproteins.
• Biopharmaceutical R&D: Used in the development and quality control of therapeutic proteins, including monoclonal antibodies and hormones.
• Enzyme Activity Assays: Serves as a co-substrate for assaying the activity of specific glycosyltransferases in diagnostic and research applications.
• Glycoengineering: A vital reagent for the chemoenzymatic remodeling of protein glycosylation patterns to optimize drug efficacy and stability.
• Biochemical Research: Fundamental tool for studying glycosylation pathways, enzyme kinetics, and carbohydrate-protein interactions.
• Diagnostic Reagent Production: Used in the formulation of kits for detecting glycosylation-related disorders.

Basic Information

Product Name	UDP-GalNAc
CAS No.	7277-98-7
Molecular Formula	C17H27N3O17P2
Molecular Weight	607.35 g/mol
Synonyms	Uridine 5'-(trihydrogen diphosphate) P'→5'-ester with 2-(acetylamino)-2-deoxy-D-galactose; UDP-N-acetyl-D-galactosamine; UDP-α-D-GalNAc; Uridine diphosphate N-acetylgalactosamine; UDP-2-Acetamido-2-deoxy-α-D-galactopyranose; UDP-Acetylgalactosamine
EINECS	Contact for details

Quality Control

Our UDP-GalNAc is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive enzymatic and research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous quality testing protocols to meet the exacting standards of pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95%
Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 5.0%
Biological Activity	Conforms (Enzymatic Test)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.