Description

5-β-Pregnan-3-Alpha, 11-Beta, 17-Triol-20-One is a high-purity steroid derivative and a key intermediate in the synthesis of complex pharmaceutical compounds. This compound matters for its role as a crucial building block in the development of corticosteroids and other specialized therapeutic agents, where precise stereochemistry is essential for biological activity. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on advanced steroid chemistry and novel drug synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent corticosteroid drugs and other steroid-based therapeutics.
• Biochemical Research: Used as a reference standard or starting material in metabolic pathway studies and steroid hormone research.
• Fine Chemical Synthesis: Serves as a chiral building block for constructing complex molecular architectures in advanced organic chemistry.
• Reference Material: Employed in analytical laboratories for method development and calibration in steroid analysis via HPLC or LC-MS.
• Process Development: Utilized in scaling up and optimizing synthetic routes for steroid production in pilot plants.

Basic Information

Product Name	5-β-Pregnan-3-Alpha, 11-Beta, 17-Triol-20-One
CAS No.	7252-91-7
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	11β,17α,21-Trihydroxy-5β-pregnan-20-one; 5β-Pregnane-3α,11β,17α-triol-20-one; 3α,11β,17α-Trihydroxy-5β-pregnan-20-one; 20-Oxo-5β-pregnane-3α,11β,17α-triol; Tetrahydrocortisol (5β-isomer); 5β-Tetrahydrocortisol; THF (5β); Urocortisol; 11β,17α,21-Trihydroxy-5β-pregnan-20-one
EINECS	Contact for details

Quality Control

Our 5-β-Pregnan-3-Alpha, 11-Beta, 17-Triol-20-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.