Description

2-Bromopropionyl Chloride is a versatile and highly reactive organic building block, primarily used as an acylating agent in fine chemical synthesis. Its value lies in its ability to efficiently introduce the 2-bromopropionyl moiety, a key intermediate for constructing more complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a critical precursor for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a bromoacetyl or propionyl backbone.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with specific functional properties.
• Peptide & Protein Modification: Employed as an acylating agent to modify amino acids, peptides, or proteins for research and bioconjugation.
• Liquid Crystal & OLED Material Production: Serves as an intermediate in the synthesis of advanced electronic and display materials.
• Dye & Pigment Manufacturing: Used in the production of complex organic dyes and pigments.
• Cross-coupling Reactions: Provides a handle for palladium-catalyzed reactions like Suzuki or Heck couplings in complex molecule assembly.
• Chemical Research & Development: A fundamental reagent for exploring new synthetic methodologies and creating novel chemical entities in R&D laboratories.

Basic Information

Product Name	2-Bromopropionyl Chloride
CAS No.	7148-74-5
Molecular Formula	C3H4BrClO
Molecular Weight	171.42 g/mol
Synonyms	2-Bromopropanoyl Chloride; α-Bromopropionyl Chloride; 2-Bromopropionic Acid Chloride; Propionyl Chloride, 2-bromo-; NSC 401122; Bromopropionyl chloride; 2-Bromo-1-chloropropan-1-one
EINECS	230-473-8

Quality Control

Our 2-Bromopropionyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat and incompatible materials. Due to its hygroscopic and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.60 - 1.65 g/mL
Boiling Point	~145-150°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.