Description

Thymidine Diphosphate-6-Deoxy-Xylo-4-Hexulose is a specialized nucleotide sugar derivative, a key intermediate in the biosynthesis of deoxysugars found in many natural products. This compound is essential for researchers and manufacturers in the life sciences sector, enabling the study and production of complex carbohydrates and glycoconjugates. It is primarily utilized in biochemical research, enzymatic synthesis, and the development of novel pharmaceuticals and diagnostic reagents.

Application

• Biochemical Research: As a critical substrate for studying the enzymes involved in deoxysugar biosynthesis pathways, such as thymidylyltransferases and dehydratases.
• Enzymatic Synthesis: Serving as a high-purity building block for the in vitro enzymatic production of complex oligosaccharides and natural product analogs.
• Pharmaceutical Development: A key intermediate in the research and development of antibiotics, anticancer agents, and other therapeutics that utilize deoxysugar moieties for biological activity.
• Glycobiology Studies: Used to investigate cell surface recognition, signaling processes, and the role of specific sugar residues in health and disease.
• Diagnostic Reagent Manufacturing: Potential use in synthesizing labeled compounds or standards for diagnostic assays targeting carbohydrate-related biomarkers.
• Academic & Industrial R&D: Fundamental tool in laboratories focused on metabolic engineering, synthetic biology, and carbohydrate chemistry.

Basic Information

Product Name	Thymidine Diphosphate-6-Deoxy-Xylo-4-Hexulose
CAS No.	7132-58-3
Molecular Formula	C₁₆H₂₄N₂O₁₆P₂
Molecular Weight	586.31 g/mol
Synonyms	TDP-6-Deoxy-D-xylo-4-hexulose; TDP-6-deoxyxylo-4-hexulose; Thymidine 5'-(trihydrogen diphosphate), P'→5'-ester with 6-deoxy-D-xylo-hex-4-ulose; dTDP-6-deoxy-D-xylo-4-hexulose; dTDP-4-keto-6-deoxy-D-glucose; 6-Deoxy-D-xylo-hexos-4-ulose, 1-(5-O-((hydroxy((((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methoxy)phosphoryl)oxy)phosphoryl)-α-D-threo-pentofuranosyl ester); TDP-4-keto-6-deoxyglucose
EINECS	Contact for details

Quality Control

Our Thymidine Diphosphate-6-Deoxy-Xylo-4-Hexulose is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the exacting standards required for research and process applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by UV)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.