Description

3'-Deoxy-5-Methyluridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, where its structural modifications can enhance metabolic stability and target specificity. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, medicinal chemistry, and the development of therapeutic oligonucleotides. Our supply ensures high purity and batch-to-batch consistency, supporting rigorous R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of antiviral and antineoplastic nucleoside analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Biochemical Tool: Employed in enzymatic studies to investigate substrate specificity and inhibition mechanisms.
• Oligonucleotide Synthesis: Serves as a modified building block for creating non-natural DNA/RNA sequences with altered properties.
• Academic & Industrial R&D: Fundamental research in organic synthesis, chemical biology, and drug discovery programs.

Basic Information

Product Name	3'-Deoxy-5-Methyluridine
CAS No.	7084-29-9
Molecular Formula	C10H14N2O5
Molecular Weight	242.23 g/mol
Synonyms	5-Methyl-2'-deoxyuridine; 5-Methyldeoxyuridine; Thymidine, 2'-deoxy-; 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil; 2'-Deoxythymidine (Note: 2'-Deoxythymidine is a common synonym, though structurally distinct, it is often referenced); dT (common abbreviation in context); 5-Methyl-2'-deoxyuridine; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-5-Methyluridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Quality standards can be aligned with cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.