Description

8-Methoxyguanosine is a modified nucleoside derivative of guanosine, featuring a methoxy group at the 8-position of the purine ring. This structural modification is of significant interest in biochemical and pharmaceutical research for its role in studying nucleic acid structure, function, and as a potential synthetic intermediate. It is primarily utilized by researchers and manufacturers in the fields of nucleoside chemistry, antiviral drug development, and molecular biology.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and repair mechanisms.
• Probe Development: Serves as a modified base for creating fluorescent or labeled probes for nucleic acid detection and sequencing.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic Research: Fundamental tool in universities and research institutes for studying RNA/DNA structure, stability, and interactions.

Basic Information

Product Name	8-Methoxyguanosine
CAS No.	7057-53-6
Molecular Formula	C11H15N5O6
Molecular Weight	313.27 g/mol
Synonyms	8-Methoxyguanosine; Guanosine, 8-methoxy-; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-methoxy-3H-purin-6-one; 8-O-Methylguanosine; 8-MeOGuo; 8-Methoxy-Guo
EINECS	Contact for details

Quality Control

Our 8-Methoxyguanosine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.