Description

3'-Deoxyuridine is a synthetic nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial building block and reference standard in the development of antiviral and anticancer agents, particularly those targeting viral polymerases and cellular DNA synthesis. It is essential for researchers and manufacturers in the fields of medicinal chemistry, molecular biology, and diagnostic reagent production who require high-purity, well-characterized biochemical intermediates.

Application

• Medicinal Chemistry Research: A key intermediate in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study polymerase activity and nucleotide metabolism pathways.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in API manufacturing.
• Diagnostic Reagent Development: Incorporated into probes and assays for virology research and clinical diagnostics.
• Academic & Institutional Research: Fundamental tool for investigating DNA/RNA synthesis mechanisms and cellular biochemistry.

Basic Information

Product Name	3'-Deoxyuridine
CAS No.	7057-27-4
Molecular Formula	C9H12N2O5
Molecular Weight	228.20 g/mol
Synonyms	3'-Deoxyuridine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2',3'-Dideoxyuridine (obsolete); Cordycepin analog; Uridine, 3'-deoxy-; ddU (historical); 3'-dUrd
EINECS	Contact for details

Quality Control

Our 3'-Deoxyuridine is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and stringent tests for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.