Description

(25S)-5β-Spirostane-1β,3β,25-Triol is a high-purity steroidal sapogenin derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and reference standard for the synthesis of novel steroid-based therapeutics and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new drug candidates, particularly in areas such as hormone regulation, anti-inflammatory agents, and metabolic studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the semi-synthesis of complex steroid drugs and novel therapeutic agents.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and compound identification.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme interactions, and receptor binding assays.
• Fine Chemical Synthesis: Serves as a versatile starting material for the preparation of specialized steroidal compounds with modified biological activity.
• Academic Research: Utilized in universities and research institutes for chemical education and exploration of new synthetic methodologies in steroid chemistry.

Basic Information

Product Name	(25S)-5β-Spirostane-1β,3β,25-Triol
CAS No.	7050-44-4
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	(25S)-Spirostane-1β,3β,25-triol; 1β,3β,25-Trihydroxy-5β-spirostane; (25S)-1β,3β,25-Trihydroxy-5β-spirostan; Tigogenin-1β,3β,25-triol; 5β-Spirostane-1β,3β,25-triol, (25S)-; 1β,3β,25-Trihydroxyspirostan-5β-ol; (25S)-1β,3β,25-Trihydroxy-5β-spirostane
EINECS	Contact for details

Quality Control

Our (25S)-5β-Spirostane-1β,3β,25-Triol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.