Description

4-Guanidinobenzoyl Chloride, Hydrochloride is a reactive chemical intermediate primarily used in the synthesis of more complex molecules. Its value lies in the guanidinobenzoyl moiety, which is a key functional group for creating compounds with specific biological activity or binding affinity. This product is essential for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly for developing protease inhibitors, peptide mimetics, and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially serine protease inhibitors.
• Peptide Chemistry: Used for the site-specific modification of peptides and the preparation of peptide-based probes.
• Bioconjugation: Facilitates the covalent attachment of guanidine-containing ligands to proteins, polymers, or surfaces for biochemical studies.
• Protease Inhibitor Development: Serves as a core structure for creating inhibitors targeting enzymes like thrombin, trypsin, and other trypsin-like proteases.
• Diagnostic Reagent Synthesis: Employed in the production of affinity labels and active-site titrants for enzymatic assays.
• Chemical Biology Research: A valuable tool for probing enzyme mechanisms and studying protein-ligand interactions.

Basic Information

Product Name	4-Guanidinobenzoyl Chloride, Hydrochloride
CAS No.	7035-79-2
Molecular Formula	C8H9Cl2N3O
Molecular Weight	234.08 g/mol
Synonyms	4-Guanidinobenzoyl Chloride HCl; p-Guanidinobenzoyl Chloride Hydrochloride; Benzoic acid, 4-(aminoiminomethyl)-, chloride, hydrochloride (1:1); 4-(Diaminomethylideneamino)benzoyl chloride hydrochloride; 4-Carbamimidoylbenzoyl chloride hydrochloride; Guanidinobenzoyl Chloride Hydrochloride; (4-Guanidinobenzoyl)chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Guanidinobenzoyl Chloride, Hydrochloride is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.