Description

(Phenylthio)Acetyl Chloride is a versatile and highly reactive organosulfur building block, essential for introducing the phenylthioacetyl moiety into target molecules. Its primary value lies in its role as a key acylating agent and intermediate in the synthesis of complex organic compounds, particularly in pharmaceutical research and development. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioether or modified peptide backbones.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive acid chloride group for derivatization.
• Peptidomimetics & Bioactive Molecule Research: Serves as a crucial building block for creating peptide analogs and other bioactive compounds with enhanced metabolic stability or binding properties.
• Material Science: Employed in the synthesis of monomers or modifiers for specialty polymers and advanced materials.
• Chemical Biology Probes: Useful for the design and synthesis of chemical probes to study enzyme function or protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the pharmaceutical and biotechnology sectors.

Basic Information

Product Name	(Phenylthio)Acetyl Chloride
CAS No.	7031-27-8
Molecular Formula	C8H7ClOS
Molecular Weight	186.66 g/mol
Synonyms	2-(Phenylthio)acetyl chloride; α-(Phenylthio)acetyl chloride; (Phenylmercapto)acetyl chloride; Phenythioacetic acid chloride; 2-Phenylsulfanylacetyl chloride; Thiophenoxyacetyl chloride; Phenylthioethanoyl chloride
EINECS	Contact for details

Quality Control

Our (Phenylthio)Acetyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the rigorous demands of research and process chemistry. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support applications requiring reliable and well-characterized chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature and classification as a strong acid/organic solvent, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.