Description

2-[(4-Chlorophenyl)Sulfanyl]Acetyl Chloride is a versatile and reactive organosulfur building block used in advanced organic synthesis. Its value lies in its bifunctional nature, combining a reactive acid chloride group with a (4-chlorophenyl)thioether moiety, enabling the construction of complex molecular architectures. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the chlorophenylsulfanyl group for bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in catalytic processes and material science.
• Polymer Modification: Employed to introduce functional thioether groups into polymer chains, altering material properties like adhesion and stability.
• Custom Chemical Synthesis: An essential reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for clients.
• Chemical Research & Development: Fundamental reagent in academic and industrial labs for exploring new organic reactions and synthesizing complex sulfur-containing molecules.

Basic Information

Product Name	2-[(4-Chlorophenyl)Sulfanyl]Acetyl Chloride
CAS No.	7031-25-6
Molecular Formula	C8H6Cl2OS
Molecular Weight	221.10 g/mol
Synonyms	2-[(4-Chlorophenyl)thio]acetyl chloride; (4-Chlorophenylthio)acetyl chloride; 2-(4-Chlorophenylsulfanyl)acetyl chloride; 4-Chlorophenylthioacetic acid chloride; α-Chloro-4-chlorophenylthioacetone? (Incorrect, verify); Acetyl chloride, 2-[(4-chlorophenyl)thio]-; 2-(p-Chlorophenylthio)acetyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-[(4-Chlorophenyl)Sulfanyl]Acetyl Chloride is produced and tested under a strict quality management system to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.