Description

3-Methylthiopropionyl Chloride is a versatile sulfur-containing acid chloride derivative, primarily used as a key building block in organic synthesis. Its high reactivity makes it an essential intermediate for introducing the 3-methylthiopropionyl moiety into target molecules. This compound is particularly valuable for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of protease inhibitors and other sulfur-containing drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the thioether linkage enhances biological activity.
• Peptide Chemistry: Serves as an acylating agent for the modification of amino acids and peptides, facilitating the introduction of lipophilic side chains.
• Flavor & Fragrance Industry: Employed in the synthesis of sulfur-containing flavor compounds that contribute to meaty, savory, or roasted notes.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers with unique properties.
• Chemical Research & Development: A valuable reagent for organic chemists in academic and industrial R&D for exploring new synthetic pathways.

Basic Information

Item	Details
Product Name	3-Methylthiopropionyl Chloride
CAS No.	7031-23-4
Molecular Formula	C4H7ClOS
Molecular Weight	138.61 g/mol
Synonyms	3-(Methylthio)propionyl chloride; β-(Methylthio)propionyl chloride; 3-Methylmercaptopropionyl chloride; 3-(Methylsulfanyl)propanoyl chloride; NSC 9375; Methyl 3-chloro-3-oxopropyl sulfide; 3-Methylthiopropanoic acid chloride
EINECS	230-300-8

Quality Control

Our 3-Methylthiopropionyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay by GC or HPLC, identity confirmation (IR, NMR), and impurity profiling to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) or as specified for the specific grade. This product is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 1.0% (individual), ≤ 2.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.