Description

5-Fluorouridine 5'-Phosphate is a fluorinated nucleotide analog of significant biochemical and pharmaceutical interest. This compound serves as a critical building block and research tool in the development of novel therapeutic agents and molecular probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleic acid chemistry, antiviral drug discovery, and cancer research. The high-purity material is essential for ensuring reliable and reproducible experimental and developmental outcomes.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases and polymerases.
• Antiviral Drug Development: Serves as a key intermediate in the synthesis of nucleotide analogs targeting viral replication mechanisms.
• Oncology Research: Investigated for incorporation into RNA or as a metabolite of chemotherapeutic agents like 5-Fluorouracil (5-FU) to study mechanisms of action.
• Molecular Biology: Employed in the synthesis of modified oligonucleotides for probing RNA structure, function, and stability.
• Pharmaceutical Intermediates: Acts as a high-value synthetic precursor for advanced active pharmaceutical ingredients (APIs).
• Diagnostic Reagent Manufacturing: Potential use in creating labeled probes for diagnostic assays.

Basic Information

Product Name	5-Fluorouridine 5'-Phosphate
CAS No.	796-66-7
Molecular Formula	C9H12FN2O9P
Molecular Weight	366.17 g/mol
Synonyms	5-Fluorouridine 5'-Monophosphate; 5-FUMP; 5-Fluorouridylic Acid; 5-Fluorouridine 5'-(Dihydrogen Phosphate); 5-Fluorouridine-5'-phosphate; 5-Fluorouridine monophosphate; 5-Fluoro-UMP; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(phosphonooxy)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-Fluorouridine 5'-Phosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and LC-MS for identity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.