Description

9H-Purine-6-Thiol, 2-Fluoro-9-β-D-Ribofuranosyl- is a fluorinated nucleoside analog, a key building block in medicinal chemistry and life science research. This compound is valued for its role as a precursor in the synthesis of antiviral and anticancer agents, particularly in the development of modified nucleosides. It is essential for pharmaceutical R&D, biotechnology, and academic laboratories focused on nucleotide chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving purine metabolism and nucleic acid processing.
• Pro-drug Development: Serves as a key moiety in the design and synthesis of nucleotide pro-drugs for enhanced therapeutic delivery.
• Antiviral Agent Synthesis: Integral to the research and development pipeline for fluorinated nucleoside-based antiviral medications.
• Life Science Reagents: Employed in the manufacture of high-purity biochemical reagents and reference standards.
• Academic & Contract Research: A valuable tool for universities and CROs conducting research in organic synthesis, medicinal chemistry, and molecular biology.

Basic Information

Product Name	9H-Purine-6-Thiol, 2-Fluoro-9-β-D-Ribofuranosyl-
CAS No.	792-16-5
Molecular Formula	C10H11FN4O4S
Molecular Weight	302.28 g/mol
Synonyms	2-Fluoro-9-β-D-ribofuranosyl-9H-purine-6-thiol; 2-Fluoroadenosine-6-thiol; 2-Fluoro-6-mercaptopurine riboside; 6-Thio-2-fluoroadenosine; 2-Fluoro-6-thiopurine ribonucleoside; 2-F-6-TPR; 2-F-6-thio-9-β-D-ribofuranosylpurine
EINECS	Contact for details

Quality Control

Our production of 9H-Purine-6-Thiol, 2-Fluoro-9-β-D-Ribofuranosyl- adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR. Certificates of Analysis (COA) detailing all specifications are available upon request to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.