Description

9-Dihydroestradiol is a key intermediate and reference standard in the synthesis and analysis of steroidal compounds. This compound is of significant importance for pharmaceutical research and development, particularly in the fields of endocrinology and hormone-related therapies. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories for method development, quality control, and as a building block in complex organic synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of more complex steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and reagent in studies related to estrogen metabolism, receptor binding, and hormonal pathways.
• Analytical Standard: Serves as a high-purity standard for analytical methods such as HPLC, GC-MS, and NMR for the identification and quantification of related steroids.
• Academic & Industrial R&D: Employed in research laboratories for investigating structure-activity relationships (SAR) and developing new therapeutic agents.
• Quality Control: Used by manufacturers to calibrate equipment and validate analytical procedures for steroidal product batches.

Basic Information

Product Name	9-Dihydroestradiol
CAS No.	791-69-5
Molecular Formula	C18H24O2
Molecular Weight	272.38 g/mol
Synonyms	9α-Dihydroestradiol; 9α-Estradiol; 9α,17β-Estradiol; 9α-Hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol; 9-Dehydroestradiol; 9-DHE2; Estra-1,3,5(10)-triene-3,17β-diol, 9α-
EINECS	Contact for details

Quality Control

Our 9-Dihydroestradiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.