Description

Dl-3-(Trifluoromethyl)Piperidine CAS NO 768-31-0 is a versatile fluorinated piperidine derivative, a key chiral building block prized for its ability to impart metabolic stability and modulate lipophilicity in complex molecules. Its trifluoromethyl group offers unique electronic and steric properties, making it a critical intermediate for advanced synthesis. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to optimize the biological activity and physicochemical profiles of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with tailored surface properties and chemical resistance.
• Chemical Biology & Proteomics: Acts as a building block for designing molecular probes and activity-based protein profiling (ABPP) agents to study enzyme function.

Basic Information

Product Name	Dl-3-(Trifluoromethyl)Piperidine
CAS No.	768-31-0
Molecular Formula	C6H10F3N
Molecular Weight	153.15 g/mol
Synonyms	3-(Trifluoromethyl)piperidine (racemic); DL-3-(Trifluoromethyl)piperidine; (±)-3-(Trifluoromethyl)piperidine; rac-3-(Trifluoromethyl)piperidine; 1-Aza-4-(trifluoromethyl)cyclohexane; 3-Trifluoromethylpiperidine; Piperidine, 3-(trifluoromethyl)-, (±)-
EINECS	Contact for details

Quality Control

Our Dl-3-(Trifluoromethyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, enantiomeric ratio (if applicable), and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.