Description

Sodium Fusidate is the sodium salt of fusidic acid, a potent steroidal antibiotic derived from the fungus *Fusidium coccineum*. This compound is valued for its exceptional efficacy against Gram-positive bacteria, particularly *Staphylococcus aureus*, including methicillin-resistant strains (MRSA). It is a critical active pharmaceutical ingredient (API) primarily utilized by pharmaceutical manufacturers in the development and production of topical and systemic antibacterial medications.

Application

• Primary Active Pharmaceutical Ingredient (API) in topical antibacterial creams, ointments, and gels for skin infections.
• Key component in oral and injectable antibiotic formulations for systemic treatment of severe staphylococcal infections.
• Used in ophthalmic preparations for treating bacterial conjunctivitis and other eye infections.
• Formulation of medicated plasters and wound dressings for localized, controlled antibiotic delivery.
• Research and development of novel antibiotic combinations to combat antimicrobial resistance (AMR).
• Reference standard in analytical laboratories for quality control and pharmacokinetic studies.

Basic Information

Product Name	Sodium Fusidate
CAS No.	751-94-0
Molecular Formula	C31H47NaO6
Molecular Weight	538.70 g/mol
Synonyms	Fusidic Acid Sodium Salt; Sodium Fusidate; Fusidin Sodium; SQ 16603; Fucidin Sodium; Ramycin Sodium Salt; 29-Norfriedelane-3,11,20-trione, 16-(acetyloxy)-3,11-dihydroxy-29-nor-8,13,18-friedelatrien-21-oic acid sodium salt
EINECS	212-036-4

Quality Control

Our Sodium Fusidate is manufactured under strict quality management systems, ensuring compliance with pharmaceutical-grade standards. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC. A detailed Certificate of Analysis (COA) confirming conformity to agreed specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 5.0%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.