Description

5'-Deoxy-5'-Fluoroadenosine is a fluorinated nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and intermediate in the synthesis of novel antiviral and anticancer agents, leveraging its modified sugar moiety to alter biological activity. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleoside metabolism and related pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Antiviral Agent Development: Investigated for its potential activity against viral polymerases due to its fluorinated structure.
• Labeled Compound Synthesis: Can be used as a starting material for preparing isotopically labeled compounds for metabolic tracing studies.
• Academic Research: Employed in universities and research institutes for studies in organic synthesis, chemical biology, and pharmacology.

Basic Information

Product Name	5'-Deoxy-5'-Fluoroadenosine
CAS No.	731-98-6
Molecular Formula	C₁₀H₁₂FN₅O₃
Molecular Weight	269.23 g/mol
Synonyms	5'-Deoxy-5'-fluoroadenosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(fluoromethyl)oxolan-2-yl]-9H-purin-6-amine; 5'-Fluoro-5'-deoxyadenosine; 5'-Deoxy-5'-fluoroadenosine; 5'-Fluoroadenosine; Adenosine, 5'-deoxy-5'-fluoro-; 5'-F-5'-dA
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5'-Fluoroadenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive. Keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.