Description

α,α-Bis(Trifluoromethyl)-p-Dimethylaminobenzyl Alcohol is a specialized fluorinated organic building block characterized by its unique combination of electron-donating dimethylamino and strongly electron-withdrawing bis(trifluoromethyl) groups. This compound matters for its role as a key intermediate in the synthesis of advanced materials and pharmaceuticals, where its structural motifs can impart significant changes in electronic properties, lipophilicity, and metabolic stability. It is primarily needed by research chemists and process development scientists in the agrochemical, pharmaceutical, and advanced materials sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel drug candidates, particularly where fluorination is desired to enhance bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a key building block for creating advanced, high-performance pesticides and herbicides with improved environmental profiles.
• Ligand and Catalyst Development: Employed in the design of specialized ligands for catalysis, leveraging the electronic effects of its substituents.
• Advanced Material Precursor: Utilized in the development of organic electronic materials, such as dyes, pigments, and nonlinear optical (NLO) materials.
• Chemical Research & Development: Acts as a versatile synthon in academic and industrial R&D for exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	α,α-Bis(Trifluoromethyl)-p-Dimethylaminobenzyl Alcohol
CAS No.	730-59-6
Molecular Formula	C11H11F6NO
Molecular Weight	287.20 g/mol
Synonyms	4-(Dimethylamino)-α,α-bis(trifluoromethyl)benzenemethanol; 4-(Dimethylamino)-α,α-bis(trifluoromethyl)benzyl Alcohol; p-(Dimethylamino)-α,α-bis(trifluoromethyl)benzyl Alcohol; 1-[4-(Dimethylamino)phenyl]-2,2,2-trifluoro-1-(trifluoromethyl)ethanol; 730-59-6; α,α-Bis(trifluoromethyl)-4-(dimethylamino)benzenemethanol
EINECS	Contact for details

Quality Control

Our α,α-Bis(Trifluoromethyl)-p-Dimethylaminobenzyl Alcohol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.