Description

1-(β-D-Ribofuranosyl)Benzimidazole is a nucleoside analog where a benzimidazole base is linked to a ribofuranose sugar moiety. This compound is of significant interest as a versatile building block and key intermediate in the synthesis of novel nucleoside derivatives and pharmaceutical agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, biochemical research, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving nucleoside-metabolizing enzymes.
• Organic Synthesis Building Block: Serves as a versatile scaffold for medicinal chemistry and the development of new chemical entities.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1-(β-D-Ribofuranosyl)Benzimidazole
CAS No.	728-01-8
Molecular Formula	C₁₂H₁₄N₂O₄
Molecular Weight	250.25 g/mol
Synonyms	1-β-D-Ribofuranosylbenzimidazole; Benzimidazole, 1-β-D-ribofuranosyl-; 1-(β-D-Ribofuranosyl)-1H-benzimidazole; NSC 401005; 1-(β-D-Ribosyl)benzimidazole; β-Ribofuranosyl benzimidazole; 1H-Benzimidazole, 1-β-D-ribofuranosyl-
EINECS	Contact for details

Quality Control

Our 1-(β-D-Ribofuranosyl)Benzimidazole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and residual solvents is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.