Description

Prilocaine is a potent, fast-acting local anesthetic of the amide type, widely recognized for its favorable safety profile and rapid metabolism. Its primary value lies in providing effective nerve blockade with a lower risk of systemic toxicity compared to other agents, making it a preferred choice in various medical and dental procedures. This compound is essential for pharmaceutical manufacturers, compounding pharmacies, and research institutions developing anesthetic formulations, topical creams, and specialized medical products.

Application

• Pharmaceutical Active Ingredient (API): Core component in injectable local anesthetics for surgical and dental procedures.
• Topical Anesthetic Formulations: Used in creams, gels, and ointments for dermal anesthesia prior to minor surgeries, laser treatments, or cosmetic procedures.
• Regional Anesthesia: Key agent in peripheral nerve blocks and epidural anesthesia, often in combination with other anesthetics like lidocaine.
• Veterinary Medicine: Employed in anesthetic protocols for surgical and diagnostic interventions in animals.
• Medical Research: Serves as a reference standard and active compound in pharmacological studies of nerve conduction and anesthetic mechanisms.
• Compounding Pharmacy: Used by specialized pharmacies to prepare customized anesthetic solutions for specific patient needs or clinical trials.

Basic Information

Product Name	Prilocaine
CAS No.	721-50-6
Molecular Formula	C13H20N2O
Molecular Weight	220.31 g/mol
Synonyms	2-(Propylamino)-o-propionotoluidide; Propitocaine; Citanest; Xylonest; Propitocainum; (±)-N-(2-Methylphenyl)-2-(propylamino)propanamide; DL-N-(2-Methylphenyl)-2-(propylamino)propionamide; NSC-77370
EINECS	211-957-7

Quality Control

Our Prilocaine is manufactured and tested under strict quality management systems to meet the rigorous standards of the pharmaceutical industry. We provide material that complies with major pharmacopoeial specifications, including USP and EP monographs. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%
Specific Optical Rotation	-0.10° to +0.10° (in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.