Description

Benzenemethanol, A,3-Bis(Trifluoromethyl)- is a specialized fluorinated benzyl alcohol derivative, recognized for its unique combination of an aromatic alcohol moiety and electron-withdrawing trifluoromethyl groups. This structure makes it a valuable and versatile advanced intermediate for synthesizing complex molecules in high-value chemical sectors. It is primarily sought after by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to modulate bioavailability, metabolic stability, and lipophilicity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a critical starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes due to their electronic properties.
• Polymer & Resin Modifier: Incorporated to introduce fluorine into polymer chains, improving chemical resistance, thermal stability, and surface properties of high-performance coatings and resins.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the steric and electronic influence of the bis(trifluoromethyl)phenyl group.
• Advanced Organic Synthesis: Utilized in cross-coupling reactions, nucleophilic substitutions, and as a protected alcohol synthon in multi-step synthetic routes for complex organic molecules.

Basic Information

Product Name	Benzenemethanol, A,3-Bis(Trifluoromethyl)-
CAS No.	721-36-8
Molecular Formula	C9H6F6O
Molecular Weight	244.14 g/mol
Synonyms	α,α,α,α',α',α'-Hexafluoro-3,5-xylenol; 3,5-Bis(trifluoromethyl)benzyl Alcohol; (3,5-Bis(trifluoromethyl)phenyl)methanol; 3,5-Di(trifluoromethyl)benzyl Alcohol; Hexafluoro-3,5-xylenol; 3,5-Bis(trifluoromethyl)benzenemethanol; α,α,α,α',α',α'-Hexafluoro-m-xylene-α,α'-diol (monoalcohol form)
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, A,3-Bis(Trifluoromethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and FTIR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.