Description

2-Fluoro-5-Nitrobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2-fluoro-5-nitrobenzoyl moiety, enabling the creation of complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, particularly for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting specific biological pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the nitro and fluorine substituents for bioactivity.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers and liquid crystal materials with specific electronic or optical properties.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate for producing complex azo dyes and high-performance pigments.
• Peptide & Protein Modification: Utilized as an acylating agent to modify amino acids, peptides, or proteins for research and diagnostic applications.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to build biaryl structures.

Basic Information

Product Name	2-Fluoro-5-Nitrobenzoyl Chloride
CAS No.	709-46-6
Molecular Formula	C7H3ClFNO3
Molecular Weight	203.56 g/mol
Synonyms	5-Nitro-2-fluorobenzoyl chloride; 2-Fluoro-5-nitrobenzoic acid chloride; 5-Nitro-2-fluorobenzoic acid chloride; 2-Fluor-5-nitrobenzoylchlorid; Benzoyl chloride, 2-fluoro-5-nitro-; 709-46-6; 2-Fluoro-5-nitrobenzoylchloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitrobenzoyl Chloride is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.